Exploration of ion selectivity in the Epithelial Sodium Channel
Start date
October 2020End date
October 2023Summary
This projects aims to investigate at a quantum level the ion selectivity filter of the epithelial sodium channel, and its affect on cell function.
Funder
Team
Surrey Lead
Dr Rebecca Lewis
Senior Lecturer in Physiology
Biography
Rebecca graduated in Bioveterinary Sciences from the University of Liverpool in 2007 and started her PhD in the same year in the School of Veterinary Science at the University of Liverpool. The main focus of Rebecca's PhD was investigating the role of ion channels and the resting membrane potential in healthy chondrocytes. This included modelling cell behaviour to determine the function of these membrane proteins in healthy cells and relating this to the osteoarthritic disease state. Rebecca's postdoctoral work continued in the Institute of Ageing and Chronic Disease at the University of Liverpool, investigating the effect of a number of pharmacological agents on cell function and ion channel expression, using electrophysiology. Rebecca's postdoctoral work continued at Liverpool, investigating the effect of inflammatory conditions on chondrocyte function. In September 2014, Rebecca joined the University of Surrey as a Lecturer in Physiology.
Research groups and centres
Our research is supported by research groups and centres of excellence.
Research themes
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