Alfie Thain
Postgraduate Research Student
Nutrition and Dietetics BSc
About
My research project
New Approaches to the Management of Pernicious Anaemia: An Overlooked, Lifelong ConditionMy PhD research is looking at Pernicious Anaemia. This lifelong complex autoimmune condition results in vitamin B12 deficiency due to autoimmune to the stomach parietal cells that produce intrinsic factor, which is vital for the absorption of vitamin B12. Following
Supervisors
My PhD research is looking at Pernicious Anaemia. This lifelong complex autoimmune condition results in vitamin B12 deficiency due to autoimmune to the stomach parietal cells that produce intrinsic factor, which is vital for the absorption of vitamin B12. Following
Publications
Alfie Thain, Kathryn Hart, Kourosh Rasekh Ahmadi (2025)Addressing the Gaps in the Vitamin B12 Deficiency 2024 NICE Guidelines: Highlighting the Need for Better Recognition, Diagnosis, and Management of Pernicious Anaemia, In: European journal of clinical nutrition Springer Nature
The 2024 NICE guidelines on vitamin B12 deficiency have significant implications for the diagnosis and management of pernicious anaemia (PA), the commonest non-dietary cause of such deficiency. This perspective discusses the guidelines in relation to PA itself, suggests that clearer diagnostic protocols are required, and calls for clinician education to improve the patient journey for those with PA.