Publications

Publications

Early-life gut bacterial community structure predicts disease risk and athletic performance in horses bred for racing. Leng, J., Moller-Levet, C., Mansergh, R.I., O'Flaherty, R., Cooke, R., Sells, P., Pinkham, C., Pynn, O., Smith, C., Wise, Z., Ellis, R., Couto Alves, A., La Ragione, R. and Proudman, C. Scientific Reports. 2024 Aug; 14(1);17124. doi: 10.1038/s41598-024-64657-6. 

Hay versus haylage: Forage type influences the equine urinary metabonome and faecal microbiota. Leng J, McNally S, Walton G, Swann J, Proudman C, Argo C, Emery S, La Ragione R, Eustace R. Equine Vet J. 2022 May;54(3):614-625. doi: 10.1111/evj.13456. Epub 2021 Jun 23. PMID: 33900659.

Metagenomic investigation of the equine faecal microbiome reveals extensive taxonomic diversity. Gilroy R, Leng J, Ravi A, Adriaenssens EM, Oren A, Baker D, La Ragione RM, Proudman C, Pallen MJ. PeerJ. 2022 Mar 23;10:e13084. doi: 10.7717/peerj.13084. PMID: 35345588; PMCID: PMC8957277.

Bugs and drugs: A systems biology approach to characterising the effect of moxidectin on the horse’s faecal microbiome. Daniels SP, Leng J, Swann JR, Proudman CJ. Anim Microbiome. 2020 Oct 14;2(1):38. doi: 10.1186/s42523-020-00056-2. PMID: 33499996; PMCID: PMC7807906.

“Bowel-on-the-bench:” Proof-of-concept of a three stage, in vitro, fermentation model of the equine large intestine. Leng J, Walton G, Swann J, Darby A, La Ragione R, Proudman C (2019). Appl Environ Microbiol. 2019 Dec 13;86(1):e02093-19. doi: 10.1128/AEM.02093-19. PMID: 31676474; PMCID: PMC6912081.

Exploration of the Fecal Microbiota and Biomarker Discovery in Equine Grass Sickness. Leng J, Proudman C, Darby A, Blow F, Townsend N, Miller A, Swann J. J Proteome Res. 2018 Mar 2;17(3):1120-1128. doi: 10.1021/acs.jproteome.7b00784. Epub 2018 Feb 2. PMID: 29364680.

Characterisation of the faecal metabolome and microbiome of Thoroughbred racehorses. Proudman CJ, Hunter JO, Darby AC, Escalona EE, Batty C, Turner C. Equine Vet J. 2015 Sep;47(5):580-6. doi: 10.1111/evj.12324. Epub 2014 Sep 29. PMID: 25041526.

Dominant components of the Thoroughbred metabolome characterised by (1) H-nuclear magnetic resonance spectroscopy: A metabolite atlas of common biofluids. Escalona EE, Leng J, Dona AC, Merrifield CA, Holmes E, Proudman CJ, Swann JR. Equine Vet J. 2015 Nov;47(6):721-30. doi: 10.1111/evj.12333. Epub 2015 Jan 28. PMID: 25130591.