Professor Guoping Lian
About
Biography
I obtained my BSc from Hunan Agriculture University in 1981 and MSc from China Agriculture University in 1984, both in Agriculture Engineering. I studied my PhD at Aston University and was awarded a PhD in 1993. Sponsored by Unilever, my PhD research is on the development of a new discrete element method (DEM) for moist granular materials and processes.
I joined Unilever in 1994 as a scientist. At Unilever, I spearheaded the development and application of computational models for in-silico design and development of novel materials, processes and products in food and cosmetics industries. Examples include pyramid teabag design, leaf tea infusion, flavour release, ice crystallization, percutaneous absorption and bioavailability.
I joined the University of Surrey in 2014. Currently I am both Professor of Chemical and Process Engineering at the University of Surrey (0.2FTE) and Science Leader of Unilever Research at Colworth (0.8FTE).
Publications
Li, L., Yang, S., Chen, T., Han, L., Lian, G. (2018) A Measurement and Modeling Study of Hair Partition of Neutral, Cationic, and Anionic Chemicals. Journal of Pharmaceutical Sciences. 107(4), pp. 1122-1130
Li, L., Yang, S., Chen, T., Han, L., Lian, G. (2018) Investigation of pH effect on cationic solute binding to keratin and partition to hair. International Journal of Cosmetic Science. 40(1), pp. 93-102
Kattou, P., Lian, G., Glavin, S., Sorrell, I., Chen, T. (2017) Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study. Pharmaceutical Research. 34(10), pp. 2036-2048
Turchi, M., Lian, G., Cai, Q., (...), Rabone, J., Noro, M. (2017) Multi-scale modelling of solute partition equilibria of micelle-water and microemulsion-water systems using molecular dynamics and COSMOtherm. Computer Aided Chemical Engineering. 40, pp. 2773-2778.
Chen, T., Lian, G., Kattou, P. (2016) In Silico Modelling of Transdermal and Systemic Kinetics of Topically Applied Solutes: Model Development and Initial Validation for Transdermal Nicotine. Pharmaceutical Research. 33(7), pp. 1602-1614
Lian, G., Seville, J. (2016) The capillary bridge between two spheres: New closed-form equations in a two century old problem. Advances in Colloid and Interface Science. 227, pp. 53-62.
Chen, L., Han, L., Saib, O., Lian, G. (2015) In Silico Prediction of Percutaneous Absorption and Disposition Kinetics of Chemicals. Pharmaceutical Research. 32(5), pp. 1779-1793.
Gordon, S., Daneshian, M., Bouwstra, J., (...), Walles, H., Lehr, C.-M. (2015) Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology. Altex. 32(4), pp. 327-378
Wang, L., Zhang, L., Lian, G. (2015) A CFD simulation of 3D air flow and temperature variation in refrigeration cabinet. Procedia Engineering. 102, pp. 1599-1611.
Wu, H., Shu, S., Yang, N., Lian,G, Zhu, S., Liu, M. (2014) Modeling of power characteristics for multistage rotor-stator mixers of shear-thinning fluids. Chemical Engineering Science. 117, pp. 173-182.
Marzinek, J.K., Bond, P.J., Lian, G., (...), Pistikopoulos, E.N., Mantalaris, A. (2014) Free energy predictions of ligand binding to an α-helix using steered molecular dynamics and umbrella sampling simulations. Journal of Chemical Information and Modeling. 54(7), pp. 2093-2104.
Zhao, Y., Marzinek, J.K., Bond, P.J., (...), Han, L., Lian, G. (2014) A study on Fe2+- α-helical-rich keratin complex formation using isothermal titration calorimetry and molecular dynamics simulation. Journal of Pharmaceutical Sciences. 103(4), pp. 1224-1232
Marzinek, J.K., Lian, G., Marzinek, J.K., (...), Bond, P.J., Noro, M.G. (2013) Molecular and thermodynamic basis for EGCG-Keratin interaction-part I: Molecular dynamics simulations. AIChE Journal. 59(12), pp. 4816-4823.
Zhao, Y., Chen, L., Han, L., (...), Bond, P.J., Noro, M.G. (2013) Molecular and thermodynamic basis for EGCG-Keratin interaction-part II: Experimental investigation. AIChE Journal. 59(12), pp. 4824-4827.
Chen, L., Han, L., Lian, G. (2013) Recent advances in predicting skin permeability of hydrophilic solutes. Advanced Drug Delivery Reviews. 65(2), pp. 295-305.
Nazir, H., Wang, L., Lian, G., (...), Liu, Y., Ma, G. (2012) Multilayered silicone oil droplets of narrow size distribution: Preparation and improved deposition on hair. Colloids and Surfaces B: Biointerfaces. 100, pp. 42-49
Zhao, Y., Chen, L., Yakubov, G., (...), Han, L., Lian, G. (2012) Experimental and theoretical studies on the binding of epigallocatechin gallate to purified porcine gastric mucin. Journal of Physical Chemistry B. 116(43), pp. 13010-13016
Wang, L., Chen, L., Han, L., Lian, G. (2012) Kinetics and equilibrium of solute diffusion into human hair. Annals of biomedical engineering. 40(12), pp. 2719-2726
Nazir, H., Lv, P., Wang, L., Lian, G, Zhu, S., Ma, G. (2011) Uniform-sized silicone oil microemulsions: Preparation, investigation of stability and deposition on hair surface. Journal of Colloid and Interface Science. 364(1), pp. 56-64
Wang, L., Chen, L., Lian, G., Han, L. (2010) Determination of partition and binding properties of solutes to stratum corneum. International Journal of Pharmaceutics. 398(1-2), pp. 114-122
Lian, G., Chen, L., Pudney, P.D.A., Mélot, M., Han, L. (2010) Modeling transdermal permeation. Part 2. Predicting the dermatopharmacokinetics of percutaneous solute. AIChE Journal. 56(10), pp. 2551-2560
Chen, L., Lian, G., Han, L. (2010) Modeling transdermal permeation. Part I. Predicting skin permeability of both hydrophobic and hydrophilic solutes. 2010 AIChE Journal 56(5), pp. 1136-1146
Tetradis-Meris, G., Rossetti, D., De Torres, C.P., (...), Lian, G., Janes, R. (2009) Novel parallel integration of microfluidic device network for emulsion formation. Industrial and Engineering Chemistry Research 48(19), pp. 8881-8889
Woollard, H.F., Billingham, J., Jensen, O.E., Lian, G. (2009) A multi-scale model for solute transport in a wavy-walled channel. Journal of Engineering Mathematics 64(1), pp. 25-48
Chen, L., Lian, G., Han, L. (2008) Use of "bricks and mortar" model to predict transdermal permeation: Model development and initial validation. Industrial and Engineering Chemistry Research 47(17), pp. 6465-6472
Zhang, Y., Lian, G., Zhu, S., (...), Wei, W., Guanghui, M. (2008) Investigation on the uniformity and stability of sunflower oil/water emulsions prepared by a Shirasu porous glass membrane. Industrial and Engineering Chemistry Research 47(17), pp. 6412-6417
Hao, D.-X., Gong, F.-L., Hu, G.-A., Lian, G., Guang-Hui, M., Su, Z. (2008) Controlling factors on droplets uniformity in membrane emulsification: Experiment and modeling analysis. Industrial and Engineering Chemistry Research 47(17), pp. 6418-6425
Lian, G., Chen, L., Han, L. (2008) An evaluation of mathematical models for predicting skin permeability. Journal of Pharmaceutical Sciences 97(1), pp. 584-598
Chen, L.-J., Lian, G.-P., Han, L.-J. (2007) Prediction of human skin permeability using artificial neural network (ANN) modelling. Acta Pharmacologica Sinica 28(4), pp. 591-600
Lian, G., Moore, S., Heeney, L. (2006) Population balance and computational fluid dynamics modelling of ice crystallisation in a scraped surface freezer. Chemical Engineering Science 61(23), pp. 7819-7826
Huang, W., Li, H., Xu, Y., Lian, G. (2006) Hydrodynamic force between two hard spheres tangentially translating in a power-law fluid. Chemical Engineering Science. 61(5), pp. 1480-1488
Weerts, A.H., Martin, D.R., Lian, G., Melrose, J.R. (2005) Modelling the hydration of foodstuffs. Simulation Modelling Practice and Theory
13(2), pp. 119-128
13(2), pp. 119-128
Jousse, F., Lian, G., Janes, R., Melrose, J. (2005) Compact model for multi-phase liquid-liquid flows in micro-fluidic devices. Lab on a Chip 5(6), pp. 646-656
Lian, G., Malone, M.E., Homan, J.E., Norton, I.T. (2004) A mathematical model of volatile release in mouth from the dispersion of gelled emulsion particles. Journal of Controlled Release 98(1), pp. 139-155
Li, H., Huang, W., Xu, Y., Lian, G. (2004) On the Squeeze Flow of a Bingham Fluid between Two Rigid Spheres. Particulate Science and Technology 22(1), pp. 1-20
Weerts, A.H., Lian, G., Martin, D.R. (2003) Modeling the hydration of foodstuffs: Temperature effects. AIChE Journal 49(5), pp. 1334-1339
Weerts, A.H., Lian, G., Martin, D. (2003) Modeling rehydration of porous biomaterials: Anisotropy effects. Journal of Food Science 68(3), pp. 937-942
Xu, Y., Kafui, K.D., Thornton, C., Lian, G. (2002) Effects of material properties on granular flow in a silo using DEM simulation. Particulate Science and Technology 20(2), pp. 109-124
Lian, G., Astill, C. (2002) Computer simulation of the hydrodynamics of teabag infusion. Food and Bioproducts Processing: Transactions of the Institution of of Chemical Engineers, Part C 80(3), pp. 155-162
Lian, G., Thiru, A., Parry, A., Moore, S. (2002) CFD simulation of heat transfer and polyphenol oxidation during tea fermentation. Computers and Electronics in Agriculture. 34(1-3), pp. 145-158
Lian, G., Xu, Y., Huang, W., Adams, M.J. (2001) On the squeeze flow of a power-law fluid between rigid spheres. Journal of Non-Newtonian Fluid Mechanics. 100(1-3), pp. 151-164
Lian, G., Thornton, C., Adams, M.J. (1998) Discrete particle simulation of agglomerate impact coalescence. Chemical Engineering Science 53(19), pp. 3381-3391
Lian, G., Harris, C.S., Evans, R., Warboys, M. (1997) Coupled heat and moisture transfer during microwave vacuum drying. Journal of Microwave Power and Electromagnetic Energy 32(1), pp. 34-44
Lian, G., Adams, M.J., Thornton, C. (1996) Elastohydrodynamic collisions of solid spheres. Journal of Fluid Mechanics 311, pp. 141-152
Lian, G., Thornton, C., Adams, M.J. (1993) A theoretical study of the liquid bridge forces between two rigid spherical bodies. Journal of Colloid And Interface Science. 161(1), pp. 138-147.